Biopharma LyoStat5 Freeze Drying Microscope

This instrument is a freeze drying microscope (FDM) used for establishing critical events such as collapse annealing and as an aid in ensuring safe, robust, and cost-efficient cycle development. The Lyostat features real-time digital video and measurement which is achieved by using a high-performance digital USB camera to determine the exact point of collapse.

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The Lyostat is an integral part of the R&D and CDMO services that we offer.

Achieve a safe, robust and cost efficient cycle development:

identify collapse/eutectic temperatures, crystallization phenomena, potential for skin/crust formation, and the effects of annealing on ice crystal growth and solute structure

Real-time digital video and measurement:

using a high performance digital USB camera to determine the exact point of collapse, capture up to 80 GB of information

Optimised Optical System:

fewer lenses than compound microscopes for clearer images, LED lamp with an efficient custom-designed electronics module and lifetime of more than 60,000 hours

Motorised vacuum control:

chamber pressure displayed in mBar, kPA or mTorr enables close investigation of the effects of pressure on sample collapse

Liquid Nitrogen Cooling System:

automatic twin-pump cooling system including 2L Dewar and flexible insulated tubing, twin pumps
for faster cooling