BioDot Sphera™ Lyobead Dispensing System

The lyobead formation system dispenses precise and accurate droplet (spheres) into an onboard liquid nitrogen bath. Our unique precision, accuracy, and throughput specifications are achieved by coupling a high-resolution adaptive pneumatic pump with our high-speed BioJet valve. A single tip can produce up to 10,000 beads per hour, while four tips can produce up to 40,000 beads per hour.

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Features & Benefits

•       Volumes: 2μL- 30μL as a single drop

•       Volume precision of < 3% CV

•       High speed, non-contact dispensing

•       Continuous (bulk) dispense

•       Scalable from R&D to production environments

•       “Step-and-repeat” and “On-the-fly” printing modes

•       Minimization of cold-chain logistics and costs

•       Lyobeads are thermally stable with a long shelf life

•       Lyobeads have lower risk of contamination

•       Lyobeads can have better reconstitution properties

Application Examples

•       Diagnostic reagents

•       Bacterial vaccines

•       PCR assay buffers and chromophores

•       Antibodies

•       Probiotics

•       Enzymes and substrates