资源中心 - 莱奥德创冻干工场

Case Study_LyoInReady LyoClear Coated Vial

| k

Case Study_LyoinMSTrack

| k

Application of Tunable Diode Laser Absorption Spectroscopy (TDLAS) to Monitoring Pharmaceutical Lyophilization

This technical brief provides an overview of Tunable Diode Laser Absorption Spectroscopy (TDLAS) and its application for monitoring freeze drying processes.

pdf | 298.14k

下载文件

Basic Principles of Freeze Drying

Freeze-drying is the removal of ice or other frozen solvents from a material through the process of sublimation and the removal of bound water molecules through the process of desorption.

pdf | 702.59k

下载文件

Equipment Capability Measurement of Laboratory Freeze-Dryers: a Comparison of Two Methods

The objective of this investigation was to evaluate two methods for measuring the maximum sublimation rate that a freeze-dryer will support—the minimum controllable pressure method and the choke point method.

pdf | 955.96k

下载文件

Failure of Glass Tubing Vials during Lyophilization

Lyophilization consists of changing a liquid pharmaceutical product into a dry solid “cake” by means of a freeze/dry process.

pdf | 2610.35k

下载文件

Freeze Drying of Vaccines – Challenges and Concepts in Formulation and Process Development

There are still millions of people who die from these diseases due to weak thermostability demanding cold chains, long-term stability issues and distribution challenges.

pdf | 486.87k

下载文件

PCR Diagnostic Kits & Freeze-Drying Considerations

Polymerase chain reaction (PCR) is a method widely used in molecular biology to make many copies of a specific DNA segment.

pdf | 430.79k

下载文件

Rational Design of Stable Lyophilized Protein Formulations

Why use lyophilization to prepare stable protein drug products?

pdf | 1598.96k

下载文件

Impact of the Freeze-Drying Process and Lyoprotectants on Nanoparticle Stability

Nanoparticles are extremely diverse, ranging from solid lipid structures to liposomes and even designs that incorporate gold/silica particles.

pdf | 284.74k

下载文件